Methamphetamine Causes Persistent Immune Dysregulation: A Cross-Species, Translational Report
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چکیده
منابع مشابه
Commentary: Methamphetamine mediates immune dysregulation in a murine model of chronic viral infection
Citation: Loftis JM (2015) Commentary: Methamphetamine mediates immune dysregulation in a murine model of chronic viral infection. A commentary on Methamphetamine mediates immune dysregulation in a murine model of chronic viral infection The recent article by Sriram et al. (2015) is one of the first studies to evaluate the effects of methamphetamine on peripheral T cell responses, in the contex...
متن کاملMethamphetamine mediates immune dysregulation in a murine model of chronic viral infection
Methamphetamine (METH) is a highly addictive psychostimulant that not only affects the brain and cognitive functions but also greatly impacts the host immune system, rendering the body susceptible to infections and exacerbating the severity of disease. Although there is gathering evidence about METH abuse and increased incidence of HIV and other viral infections, not much is known about the eff...
متن کاملJPET #188433 Methamphetamine self-administration causes persistent striatal dopaminergic alterations and mitigates the deficits caused by a subsequent methamphetamine exposure
Preclinical studies have demonstrated that repeated methamphetamine (METH) injections (referred to herein as a “binge” treatment) cause persistent dopaminergic deficits. A few studies have also examined the persistent neurochemical impact of METH self-administration in rats, but with variable results. These latter studies are important because: 1) of their relevance to the study of METH abuse; ...
متن کاملMethamphetamine self-administration causes persistent striatal dopaminergic alterations and mitigates the deficits caused by a subsequent methamphetamine exposure.
Preclinical studies have demonstrated that repeated methamphetamine (METH) injections (referred to herein as a "binge" treatment) cause persistent dopaminergic deficits. A few studies have also examined the persistent neurochemical impact of METH self-administration in rats, but with variable results. These latter studies are important because: 1) they have relevance to the study of METH abuse;...
متن کاملDopamine receptors and the persistent neurovascular dysregulation induced by methamphetamine self-administration in rats.
Recently abstinent methamphetamine (Meth) abusers showed neurovascular dysregulation within the striatum. The factors that contribute to this dysregulation and the persistence of these effects are unclear. The current study addressed these knowledge gaps. First, we evaluated the brains of rats with a history of Meth self-administration following various periods of forced abstinence. Micro-compu...
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ژورنال
عنوان ژورنال: Neurotoxicity Research
سال: 2010
ISSN: 1029-8428,1476-3524
DOI: 10.1007/s12640-010-9223-x